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News
ViaNautis expands into spinal cord injury with SCI Ventures backing for polyNaut platform
3+ day, 17+ hour ago (413+ words) AllSci Cambridge, UK-based ViaNautis Bio has secured investment from SCI Ventures to expand its non-viral genetic medicine delivery platform into chronic spinal cord injury (CSI). Financial terms of the investment were not disclosed. SCI Ventures describes itself as a mission-driven…...
IDEAYA, Servier expand darovasertib into Phase III adjuvant uveal melanoma
4+ day, 15+ hour ago (344+ words) allsci.com San Francisco-based IDEAYA Biosciences (Nasdaq: IDYA) and France-based Servier announced that the first patient has been dosed in OptimUM-11, a global Phase III registrational trial evaluating darovasertib in combination with crizotinib as adjuvant therapy for patients with primary…...
BrainChild Bio raises USD 116m to advance CAR T therapy for pediatric brain cancer
5+ day, 18+ hour ago (440+ words) AllSci Seattle-based BrainChild Bio, Inc., a clinical-stage company developing CAR T cell therapies for central nervous system tumors, has closed a USD 116 million Series A financing to fund a pivotal registrational trial in diffuse intrinsic pontine glioma (DIPG), a uniformly…...
GSK advances dual-antigen mRNA flu vaccine to Phase III after positive Phase II
1+ week, 4+ day ago (398+ words) AllSci Positive Phase II data for GSK's mRNA seasonal influenza vaccine candidate FLUm3HA.b-3NA have cleared the bar for a Phase III efficacy trial, with the UK giant reporting higher immune responses against all tested influenza strains compared to both standard-dose and…...
Lilly snaps up Merida in USD 2.9b autoimmune deal
1+ week, 5+ day ago (577+ words) AllSci Eli Lilly has agreed to acquire Cambridge, Massachusetts-based Merida Biosciences, Inc., a private precision immunology company, for up to USD 2.875 billion in cash, adding a precision immunology platform led by the Phase I antibody therapeutic MER511, designed to selectively deplete…...
CStone to put EGFR/HER3 bispecific ADC to first-in-human test in China
3+ week, 2+ day ago (117+ words) CStone said preclinical studies showed CS5007 had antitumor activity across models with different levels of EGFR and HER3 expression. Its ability to differentiate clinically from iza-bren and other ADCs targeting EGFR-family receptors will depend on the therapeutic window generated by its antibody,…...